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Garlic and Diabetes

Garlic and Blood Sugar

Common Names: Allium, Garlic, Rustic Treacle, Stinking Rose

Garlic is one of the earth's greatest health tonics and does indeed have scientifically-proven medicinal properties. It contains a substance called Allicin, which has anti-bacterial properties that are equivalent to mildpenicillin. Garlic contains many sulfur compounds which detoxify the body, boost the immune system, lower blood pressure and improve circulation. Garlic has also demonstrated anti-cancer, antibacterial, anti-fungal and anti-oxidant effects.

Important Research and opinions on Garlic and diabetes.

Garlic Chemical Tablet Treats Diabetes 1 and 2
A drug based on a chemical found in garlic can treat diabetes types I and II when taken as a tablet, a study in the new Royal Society of Chemistry journal Metallomics says. When Hiromu Sakurai and colleagues from the Suzuka University of Medical Science, Japan, gave the drug orally to type I diabetic mice, they found it reduced blood glucose levels.

The drug is based on vanadium and allixin, a compound found in garlic, and its action described in an Advance Article from Metallomics available free online from today. The first issue of the new journal will be published in 2009.

In previous work they had discovered the vanadium-allixin compound treated both diabetes types when injected, but this new study shows the drug has promise as an oral treatment for the disease.

Type I diabetes (insulin dependent) is currently treated with daily injections of insulin, while type II (non-insulin dependent) is treated with drugs bearing undesirable side-effects – the authors note neither treatment is ideal.
The researchers aim to test the drug in humans in future work.
Read more at: http://www.dietaryfiberfood.com/herbs/garlic-diabetes.php

Garlic report
Its reputation as a medicinally valuable plant has been confirmed time and again, as well. Studies have shown garlic to be beneficial in lowering cholesterol levels, reducing raised blood pressure, protecting the body against heart disease and cancer, and enhancing immune function. Garlic has also proven to be a beneficial part of a diabetic diet.

Read more: http://findarticles.com/p/articles/mi_m0FKA/is_n9_v58/ai_18643366/

Garlic and ALLICIN
There can be many components inside garlic, such as APDS-allyl propyl disulphide, ALLICIN-diallyl disulphide oxide, flavonoids and many others. But the component, which has a great impact for your health is ALLICIN.
In fact, this is responsible for the particular taste and odor of garlic too.
Actually, these components compete with insulin for insulin-inactivating sites in the liver. This results in no insulin inactivation. Thus the free insulin is increased. In fact, studies have referred the administration of 100-125 mg/kg to fasting humans resulted in a wonderful decrease of blood glucose levels and in a raise of serum insulin.

Read more at: http://www.all-about-beating-diabetes.com/garlic-and-diabetes.html

Garlic in diabetic drugs
ScienceDaily (Nov. 19, 2008) — A drug based on a chemical found in garlic can treat diabetes types I and II when taken as a tablet, a study in the new Royal Society of Chemistry journal Metallomics says. In previous work they had discovered the vanadium-allixin compound treated both diabetes types when injected, but this new study shows the drug has promise as an oral treatment for the disease.
Read more at: http://www.sciencedaily.com/releases/2008/11/081119084835.htm

UK researchers are to test whether garlic could be used to counter diabetes, promising renewed interest in one of the most well-established dietary supplement products.
The scientists at Manchester Metropolitan University believe liquid garlic could prevent the damage to the eyes, kidneys, blood vessels and skin of diabetes patients caused by high sugar levels in a process known as glycation.
"Garlic in its liquid form has proved a potent block on glycation in a series of in-vitro tests we have conducted," said Dr Nessar Ahmed, molecular biologist at the university's department of biological sciences.
Read more at: http://www.nutraingredients.com/Research/Garlic-goes-under-trial-for-diabetes-management 

Onion and Garlic ( Allium cepa and Allium sativum)
Onion and garlic have significant blood sugar lowering action. The principal active ingredients are believed to be allyl propyl disulphide (APDS) and diallyl disulphide oxide (allicin), although other constitutents such as flavonoids may play a role as well. 
Experimental and clinical evidence suggests that APDS lowers glucose levels by competing with insulin for insulin-inactivating sites in the liver. This results in an increase of free insulin. APDS administered in doses of 125 mg/ kg to fasting humans was found to cause a marked fall in blood glucose levels and an increase in serum insulin. Allicin doses of 100 mg/kg produced a similar effect.  Onion extract was found to reduce blood sugar levels during oral and intravenous glucose tolerance. The effect improved as the dosage was increased; however, beneficial effects were observed even for low levels that used in the diet (eg., 25 to 200 grams). The effects were similar in both raw and boiled onion extracts. Onions affect the hepatic metabolism of glucose and/or increases the release of insulin, and/or prevent insulin's destruction. 
The additional benefit of the use of garlic and onions are their beneficial cardiovascular effects. They are found to lower lipid levels, inhibit platelet aggregation and are antihypertensive. So, liberal use of onion and garlic are recommended for diabetic patients. 

Aged Garlic Extract May Help Manage Diabetes
Recent tests already show hope that aged garlic extract can prevent damage to eyes, kidneys, blood vessels and skin.
Can aged garlic extract really help diabetics preserve their vision? People who have diabetes often suffer from damage to their eyes, kidneys, blood vessels and skin. This is caused by high sugar levels in a process called glycation. Researchers at Manchester University in England have already shown that garlic, in liquid form, may be a potent block on glycation in the lab. Now the same researchers will study the effect of liquid Kyolic® Aged Garlic Extract in a clinical trial involving 70 patients with Type 2 diabetes, the most common form of diabetes.
Read more at: http://vitanetonline.com/forums/1/Thread/229

Other research on garlic
Similar researches were carried out in India and Saudi Arabia, and the scientists confirmed blood glucose-lowering properties of garlic. The beneficial therapeutic effects of garilc is contributed to its antioxidative action. The vanadium-allixin compounds assisted greatly in keeping hormonal insuline leves under control and improving the function of thyroid gland. Japanese scientists underine that using this new tablet based on the beneficial properties of garlic is much safer and more effective than using the existing traditional treatment for type I diabetes: daily insulin injections. The results of the studies were publshed in a magazine of the new Royal Society of Chemistry in the beginning of the year.

Read more at: http://guide2herbalremedies.com/garlic-diabetes/    


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